Given its favorable reproductive safety profile, lamotrigine is a reasonable option for women who require treatment with a mood stabilizer during pregnancy.
Does lamotrigine cause birth defects?
A study published last year in the journal Neurology also found that babies born to pregnant women taking lamotrigine appeared not be at an increased risk of birth defects, such as cleft lip, cleft palate or clubfoot.
What pregnancy category is lamotrigine?
Safety of Psychiatric Medications During Pregnancy and Lactation
|Drug||FDA pregnancy category*|
|Valproic acid (Depakene)||D|
Can Lamictal cause a miscarriage?
There is currently no proof that lamotrigine use in pregnancy causes miscarriage or stillbirth.
What bipolar medications are safe during pregnancy?
Treatment Options for Women With Bipolar Disorder During Pregnancy
- Antiepileptic medications including carbamazepine, lamotrigine, and valproic acid; and.
- Atypical antipsychotic medications: aripiprazole, olanzapine, quetiapine, risperidone, and ziprasidone.
Does lamotrigine cross the placenta?
Lamotrigine has a good tolerability and safety profile, but is known to cross the placenta. There is no consensus regarding its use in pregnancy.
What is the safest antidepressant for pregnancy?
Antidepressants that are considered safer include:
- Fluoxetine (Prozac, Sarafem)
- Citalopram (Celexa)
- Sertraline (Zoloft)
- Amitriptyline (Elavil)
- Desipramine (Norpramin)
- Nortriptyline (Pamelor)
- Bupropion (Wellbutrin)
Does Lamictal deplete folic acid?
Anticonvulsants that do not induce cytochrome P450 enzymes, such as lamotrigine (Lamictal), are not associated with low levels of folic acid.
Does lamotrigine cause weight gain?
Low risk of weight gain: Lamotrigine (Lamictal) is most likely to cause weight loss. However, it can also cause weight gain. Other common side effects of this drug include: headache.
What is Category D in pregnancy?
Category D. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease in which safer drugs cannot be used or are ineffective).
Does Lamictal make it hard to get pregnant?
There’s no firm evidence that lamotrigine affects female fertility. For some men with epilepsy, epilepsy medicines can reduce their levels of testosterone. It does not affect everyone, but it could make you less fertile.
How safe is lamotrigine?
Lamotrigine (Lamictal) has been associated with a rare, but serious and life-threatening adverse reaction called hemophagocytic lymphohistiocytosis (HLH), which can lead to multi-organ failure resulting in hospitalization or death, particularly if diagnosis and treatment are delayed.
Is Lamictal safe long term?
To date, there are no known problems associated with long term use of lamotrigine. It is a safe and effective medication when used as directed.
Should a bipolar woman have a baby?
Most women with bipolar disorder have a healthy pregnancy and baby, but there are some risks to be aware of. You may become unwell during your pregnancy, but the risk is higher after you give birth. Women with bipolar disorder are more likely to get: postnatal depression.
How do you deal with bipolar during pregnancy?
Treating bipolar disorder during pregnancy is difficult due to many factors, the primary one being an absence of risk-free options. Bipolar disorder is often treated with polytherapy, but doctors should strive to maintain monotherapy by eliminating those medications that are either highly teratogenic or not essential.
Is Abilify safe to take during pregnancy?
Based on the available studies, aripiprazole use during pregnancy is not likely to be a high risk for birth defects. Two small studies did not show an increased chance of birth defects when women took aripiprazole during pregnancy.